Released on 29/10/2016

Key Learning Points

  • Anticholinergic Syndrome
  • Further management of serotonin syndrome
  • Initial Evaluation of a Patient presenting with a seizure
  • Initial management of serotonin syndrome
  • Lumbar Puncture and Seizures with Fever
  • Medications associated with serotonin syndrome
  • Meningitis
  • Serotonin Syndrome
  • Tylenol


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2. ABLES AZ, NAGUBILLI R. Prevention, recognition, and management of serotonin syndrome. Am Fam Physician [online] 2010 May 1, 81(9):1139-42 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/20433130
3. FRANK C. Recognition and treatment of serotonin syndrome Can Fam Physician [online] 2008 Jul, 54(7):988-992 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464814
4. ENER RASIH ATILLA, MEGLATHERY SHARON B., DECKER WILLIAM A. VAN, GALLAGHER ROLLIN M.. Serotonin Syndrome and Other Serotonergic Disorders: Table 1. Pain Med [online] December, 4(1):63-74 [viewed 22 July 2016] Available from: doi:10.1046/j.1526-4637.2003.03005.x
5. CORALLO CE, WHITFIELD A, WU A. Anticholinergic syndrome following an unintentional overdose of scopolamine Ther Clin Risk Manag [online] 2009 Sep 15:719-723 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747390
6. WATKINS JW, SCHWARZ ES, ARROYO-PLASENCIA AM, MULLINS ME, ON BEHALF OF THE TOXICOLOGY INVESTIGATORS CONSORTIUM INVESTIGATORS. The Use of Physostigmine by Toxicologists in Anticholinergic Toxicity J Med Toxicol [online] 2014 Dec 16, 11(2):179-184 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469718
7. BOYLE JS, BECHTEL LK, HOLSTEGE CP. Management of the critically poisoned patient Scand J Trauma Resusc Emerg Med [online] 2009 Jun 29:29 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720377
8. VOLPI-ABADIE J, KAYE AM, KAYE AD. Serotonin Syndrome Ochsner J [online] 2013 Winter, 13(4):533-540 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865832
9. Meningitis Paediatr Child Health [online] 2001 Mar, 6(3):126-127 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804524
10. IHEKWABA UK, KUDESIA G, MCKENDRICK MW. Clinical features of viral meningitis in adults: significant differences in cerebrospinal fluid findings among herpes simplex virus, varicella zoster virus, and enterovirus infections. Clin Infect Dis [online] 2008 Sep 15, 47(6):783-9 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/18680414
11. BROUWER MC, TUNKEL AR, VAN DE BEEK D. Epidemiology, Diagnosis, and Antimicrobial Treatment of Acute Bacterial Meningitis Clin Microbiol Rev [online] 2010 Jul, 23(3):467-492 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901656
12. TAKESHITA J, LITZINGER MH. Serotonin Syndrome Associated With Tramadol Prim Care Companion J Clin Psychiatry [online] 2009, 11(5):273 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781045
13. MESTRES J, SEIFERT S, OPREA T. Linking Pharmacology to Clinical Reports: Cyclobenzaprine and Its Possible Association With Serotonin Syndrome Clin Pharmacol Ther [online] 2011 Oct 5, 90(5):10.1038/clpt.2011.177 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809033
14. STEERING COMMITTEE ON QUALITY IMPROVEMENT AND MANAGEMENT, SUBCOMMITTEE ON FEBRILE SEIZURES AMERICAN ACADEMY OF PEDIATRICS. Febrile seizures: clinical practice guideline for the long-term management of the child with simple febrile seizures. Pediatrics [online] 2008 Jun, 121(6):1281-6 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/18519501
15. GRAVES RC, OEHLER K, TINGLE LE. Febrile seizures: risks, evaluation, and prognosis. Am Fam Physician [online] 2012 Jan 15, 85(2):149-53 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/22335215
16. POHLMANN-EDEN B, BEGHI E, CAMFIELD C, CAMFIELD P. The first seizure and its management in adults and children BMJ [online] 2006 Feb 11, 332(7537):339-342 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363913