Bruised

Released on 12/02/2016

Key Learning Points

  • Auer Rods
  • Band Keratopathy
  • Bone Marrow Biopsy
  • CNS Involvement in ALL
  • Daunorubicin, Vincristine, and Prednisolone
  • Malignant Hypercalcemia
  • Metastatic activity of ALL

References

1. BAIN BJ. Auer rods or McCrae rods? Am J Hematol [online] 2011 Aug, 86(8):689 [viewed 12 January 2016] Available from: doi:10.1002/ajh.21978 2. ABRAMSON N, MELTON B. Leukocytosis: basics of clinical assessment. Am Fam Physician [online] 2000 Nov 1, 62(9):2053-60 [viewed 12 January 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/11087187 3. CONTER V, RIZZARI C, SALA A, CHIESA R, CITTERIO M, BIONDI A. Acute Lymphoblastic Leukemia Orphanet Encyclopedia. December 2004. [viewed 12 January 2016] Available from: http://www.orpha.net/data/patho/GB/uk-ALL.pdf 4. NASCIMENTO H, YASUTA MK, MARQUEZAN MC, SALOMãO GH, GONZáLEZ D, FRANCESCONI C, MUCCIOLI C, BELFORT R JR. Uveitic band keratopathy: child and adult J Ophthalmic Inflamm Infect [online] 1/01/01 00:00:35 [viewed 13 January 2016] Available from: doi:10.1186/s12348-015-0062-z 5. O'CONNOR GR. Calcific band keratopathy. Trans Am Ophthalmol Soc [online] 1972/01/01 00:00:58-81 [viewed 13 January 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310442 6. ŽOFKOVá I. Hypercalcemia. Pathophysiological aspects. Physiol Res [online] 2015 Nov 24 [viewed 14 January 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/26596315 7. BAHOUSH G, MIRI-ALIABAD G. Severe Hypercalcemia: A Rare and Unusual Presentation of Childhood Acute Lymphoblastic Leukemia Int J Hematol Oncol Stem Cell Res [online] 2014/01/01 00:00, 8(2):38-40 [viewed 14 January 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003442 8. PERCIVAL RC, YATES AJ, GRAY RE, NEAL FE, FORREST AR, KANIS JA. Role of glucocorticoids in management of malignant hypercalcaemia. Br Med J (Clin Res Ed) [online] 1984/08/04 00:00, 289(6440):287 [viewed 14 January 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1442158 9. STEWART ANDREW F.. Hypercalcemia Associated with Cancer. N Engl J Med [online] 2005 January, 352(4):373-379 [viewed 14 January 2016] Available from: doi:10.1056/NEJMcp042806 10. 1. SISON E. A. R., SILVERMAN L. B.. CNS prophylaxis in pediatric acute lymphoblastic leukemia. Hematology [online] December, 2014(1):198-201 [viewed 21 January 2016] Available from: doi:10.1182/asheducation-2014.1.198 11. HAMDI A, MAWAD R, BASSETT R, DI STASI A, FERRO R, AFROUGH A, RAM R, DABAJA B, RONDON G, CHAMPLIN R, SANDMAIER BM, DONEY K, BAR M, KEBRIAEI P. Central Nervous System Relapse in Adults with Acute Lymphoblastic Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation Biol Blood Marrow Transplant [online] 2014/11/01 00:00, 20(11):1767-1771 [viewed 21 January 2016] Available from: doi:10.1016/j.bbmt.2014.07.005 12. SUNG SH, JANG IS. Isolated Central Nervous System Relapse of Acute Lymphoblastic Leukemia Brain Tumor Res Treat [online] 2014/10/01 00:00, 2(2):114-118 [viewed 22 January 2016] Available from: doi:10.14791/btrt.2014.2.2.114 13. PUI CHING-HON, EVANS WILLIAM E.. Treatment of Acute Lymphoblastic Leukemia. N Engl J Med [online] 2006 January, 354(2):166-178 [viewed 14 January 2016] Available from: doi:10.1056/NEJMra052603 14. COOPER SL, BROWN PA. Treatment of Pediatric Acute Lymphoblastic Leukemia Pediatr Clin North Am [online] 2015/02/01 00:00, 62(1):61-73 [viewed 14 January 2016] Available from: doi:10.1016/j.pcl.2014.09.006 15. ALEXANDER S.. Clinically defining and managing high-risk pediatric patients with acute lymphoblastic leukemia. Hematology [online] December, 2014(1):181-189 [viewed 17 January 2016] Available from: doi:10.1182/asheducation-2014.1.181 16. TRENDOWSKI MATTHEW. The inherent metastasis of leukaemia and its exploitation by sonodynamic therapy. Critical Reviews in Oncology/Hematology [online] 2015 May, 94(2):149-163 [viewed 23 January 2016] Available from: doi:10.1016/j.critrevonc.2014.12.013